GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs11723261 | 1 | rs61795001 | chr4:242057 | ZNF718 | chr4:53272-156488:+ | 0.34 | 4.54 | 7.4E-6 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs11723261 | 1 | rs61795002 | chr4:242797 | ZNF718 | chr4:53272-156488:+ | 0.34 | 4.55 | 7.29E-6 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs11723261 | 1 | rs61795006 | chr4:253601 | ZNF718 | chr4:53272-156488:+ | 0.29 | 4.06 | 5.94E-5 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs11723261 | 1 | rs61795007 | chr4:255264 | ZNF718 | chr4:53272-156488:+ | 0.28 | 4.03 | 6.69E-5 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs17030613 | 1 | rs61818802 | chr1:113181739 | ST7L | chr1:113066142-113162405:- | 0.41 | 5.91 | 7.39E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs61826828 | 1 | rs61826828 | chr1:174015261 | ANKRD45 | chr1:173577475-173639001:- | 0.29 | 3.94 | 9.77E-5 | Schizophrenia |
| BLCA | cis | rs56322409 | 1 | rs61871790 | chr10:97391223 | ENTPD1 | chr10:97471536-97637022:+ | 0.19 | 4.84 | 1.87E-6 | Blood metabolite levels |
| BLCA | cis | rs56322409 | 1 | rs61871792 | chr10:97397586 | ENTPD1 | chr10:97471536-97637022:+ | 0.19 | 4.94 | 1.15E-6 | Blood metabolite levels |
| BLCA | cis | rs56322409 | 1 | rs61871793 | chr10:97407738 | ENTPD1 | chr10:97471536-97637022:+ | 0.2 | 4.89 | 1.46E-6 | Blood metabolite levels |
| BLCA | cis | rs12908161 | 1 | rs62019464 | chr15:85294469 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.12 | 4.63E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs62019469 | chr15:85321220 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.18 | 3.68E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs62021219 | chr15:85256159 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.17 | 3.71E-5 | Schizophrenia |
| BLCA | cis | rs4776059 | 1 | rs62023352 | chr15:52889448 | ARPP19 | chr15:52839432-52861364:- | 0.21 | 3.84 | 0.000146 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs62026530 | chr15:84775840 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.65 | 4.65E-6 | Schizophrenia |
| BLCA | cis | rs9902453 | 1 | rs62070312 | chr17:28438877 | EFCAB5 | chr17:28256874-28435469:+ | 0.23 | 3.91 | 0.000109 | Coffee consumption (cups per day) |